Evaluation of the Eighth Edition of the American Joint Committee on Cancer TNM Staging System for Gastric Cancer: An Analysis of 7371 Patients in the SEER Database.

ABSTRACT:

Objective

To investigate the validity of the 8^th edition of the American Joint Committee on Cancer (AJCC) TNM staging system for gastric cancer.

Methods

The clinicopathologic data of 7371 patients who were diagnosed with gastric cancer and had 16 or more involved lymph nodes (LNs) were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database and retrospectively reviewed.

Results

Stage migration occurred primarily during stage III between the 7^th and 8^th edition TNM staging systems. Stages IIIB and IIIC in the 7^th edition staging system were divided in the 8^th edition and had obvious differences in survival rates (both P < 0.001). The 8^th edition TNM stages IIIC and IV showed

SUBMITTER: Cao LL 

PROVIDER: S-EPMC6487090 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature