Psychotic-Like Experiences in Offspring of Parents With Bipolar Disorder and Community Controls: A Longitudinal Study.

ABSTRACT:

Objective

To compare the prevalence and risk factors associated with psychotic-like experiences (PLE) in offspring of parents with bipolar disorder (BP) and offspring of community control parents.

Method

Delusional and hallucinatory subclinical psychotic experiences were evaluated at intake and longitudinally in a cohort study of 390 offspring of BP parents and 247 offspring of control parents; all offspring were between 6 and 18 years of age. The sample was followed up every 2.5 years on average for 8.3 years. Of the sample, 91.7% completed at least one follow-up. Risk factors at intake and at each assessment until the onset of PLE were analyzed using survival models.

Results

In all, 95 offspring (14.9%) reported PLE at some point of the study, 16.9% of BP parents an

SUBMITTER: Mendez I 

PROVIDER: S-EPMC6487225 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature