Chronoprints: Identifying Samples by Visualizing How They Change over Space and Time.

ABSTRACT: The modern tools of chemistry excel at identifying a sample, but the cost, size, complexity, and power consumption of these instruments often preclude their use in resource-limited settings. In this work, we demonstrate a simple and low-cost method for identifying a sample based on visualizing how the sample changes over space and time in response to a perturbation. Different types of perturbations could be used, and in this proof-of-concept we use a dynamic temperature gradient that rapidly cools different parts of the sample at different rates. We accomplish this by first loading several samples into long parallel channels on a "microfluidic thermometer chip." We then immerse one end of the chip in liquid nitrogen to create a dynamic temperature gradient along the channels, and we use an

SUBMITTER: McKenzie BA 

PROVIDER: S-EPMC6487450 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature