Pre-eclampsia and risk of later kidney disease: nationwide cohort study.

ABSTRACT:

Objective

To investigate associations between pre-eclampsia and later risk of kidney disease.

Design

Nationwide register based cohort study.

Setting

Denmark.

Population

All women with at least one pregnancy lasting at least 20 weeks between 1978 and 2015.

Main outcome measure

Hazard ratios comparing rates of kidney disease between women with and without a history of pre-eclampsia, stratified by gestational age at delivery and estimated using Cox regression.

Results

The cohort consisted of 1 072 330 women followed for 19 994 470 person years (average 18.6 years/woman). Compared with women with no previous pre-eclampsia, those with a history of pre-eclampsia were more likely to develop chronic renal conditions: hazard ratio 3.93 (95% confidence inte

SUBMITTER: Kristensen JH 

PROVIDER: S-EPMC6487675 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature