Broad phylogeny and functionality of cellulosomal components in the bovine rumen microbiome.

ABSTRACT: The cellulosome is an extracellular multi-enzyme complex that is considered one of the most efficient plant cell wall-degrading strategies devised by nature. Its unique modular architecture, achieved by high affinity and specific interaction between protein modules (cohesins and dockerins) enables formation of various enzyme combinations. Extensive research has been dedicated to the mechanistic nature of the cellulosome complex. Nevertheless, little is known regarding its distribution and abundance among microbes in natural plant fibre-rich environments. Here, we explored these questions in bovine rumen microbial communities, specialized in efficient degradation of lignocellulosic plant material. We bioinformatically screened for cellulosomal modules in this complex environment using a pre

SUBMITTER: Bensoussan L 

PROVIDER: S-EPMC6487960 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature