Mapping Structure-Function Relationships in the Brain.

ABSTRACT: Mapping the structural and functional connectivity of the brain is a major focus of systems neuroscience research and will help to identify causally important changes in neural circuitry responsible for behavioral dysfunction. Several methods for examining brain activity in humans have been extended to rodent and monkey models in which molecular and genetic manipulations exist for linking to human disease. In this review, which is part of a special issue focused on bridging brain connectivity information across species and spatiotemporal scales, we address mapping brain activity and neural connectivity in rodents using optogenetics in conjunction with either functional magnetic resonance imaging or optical intrinsic signal imaging. We chose to focus on these techniques because they are cap

SUBMITTER: Snyder AZ 

PROVIDER: S-EPMC6488459 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature