Sleep Disturbances and Inflammatory Biomarkers in Schizophrenia: Focus on Sex Differences.

ABSTRACT:

Objectives

Persons with schizophrenia, and women in particular, are at high risk for sleep disturbances and inflammatory activation. The sleep-inflammation link has been reported to be stronger in women within the general population. This study sought to examine the sleep-inflammation link in persons with schizophrenia and its relationship with demographic, clinical and cognitive variables.

Design

Cross-sectional case-control study.

Participants

Community-dwelling outpatients with schizophrenia (N=144, 46% women) and non-psychiatric comparison (NC) participants (N=134, 52% women), age 26-65 years.

Measurements

Reported sleep disturbances (sleep quality and duration), and mental and physical health were assessed. Cognitive assessments included executive function

SUBMITTER: Lee EE 

PROVIDER: S-EPMC6489497 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature