Consumption of a defined, plant-based diet reduces lipoprotein(a), inflammation, and other atherogenic lipoproteins and particles within 4 weeks.

ABSTRACT:

Background

Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein and is minimally effected by lifestyle changes. While some drugs can reduce Lp(a), diet has not consistently shown definitive reduction of this biomarker. The effect of consuming a plant-based diet on serum Lp(a) concentrations have not been previously evaluated.

Hypothesis

Consumption of a defined, plant-based for 4 weeks reduces Lp(a).

Methods

Secondary analysis of a previous trial was conducted, in which overweight and obese individuals (n = 31) with low-density lipoprotein cholesterol concentrations >100 mg/dL consumed a defined, plant-based diet for 4 weeks. Baseline and 4-week labs were collected. Data were analyzed using a paired samples t-test.

Results

Significant reductions were obse

SUBMITTER: Najjar RS 

PROVIDER: S-EPMC6489854 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature