Does obesity affect the outcomes in takotsubo cardiomyopathy? Analysis of the Nationwide Inpatient Sample database, 2010-2014.

ABSTRACT:

Background

Obesity can lead to increased oxidative stress which is one of the proposed mechanisms in the etiopathogenesis of takotsubo cardiomyopathy (TCM).

Hypothesis

The presence of obesity adversely impacts clinical outcomes in TCM patients.

Methods

We queried the Nationwide Inpatient Sample database (2010-2014) to identify adult patients admitted with a principal diagnosis of TCM with and without obesity. We compared the categorical and continuous variables by Pearson χ² and Student t test, respectively, in propensity-score matched cohorts.

Results

The study cohort comprised 612 obese TCM (weighted n = 3034) and 5696 nonobese TCM (weighted n = 28 186) patients. Obese TCM patients were more often younger and private-insurance enrollees. Cardiac co

SUBMITTER: Desai R 

PROVIDER: S-EPMC6489855 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature