Left ventricular end-diastolic volume predicts exercise capacity in patients with a normal ejection fraction.

ABSTRACT:

Background

Exercise capacity is a powerful predictor of all-cause mortality. The duration of exercise with treadmill stress testing is an important prognostic marker in both healthy subjects and patients with cardiovascular disease. Left ventricular (LV) structure is known to adapt to sustained changes in level of physical activity.

Hypothesis

Poor exercise capacity in patients with a preserved LV ejection fraction (LVEF) should be reflected in smaller LV dimensions, and a normal exercise capacity should be associated with larger LV dimensions, irrespective of comorbidities.

Methods

This hypothesis was first tested in a cross-sectional analysis of 201 patients with normal chamber dimensions and preserved LVEF who underwent a clinically indicated treadmill stress echoc

SUBMITTER: Nambiar L 

PROVIDER: S-EPMC6489861 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature