Predictors of long-term mortality with cardiac resynchronization therapy in mild heart failure patients with left bundle branch block.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) is highly beneficial in patients with heart failure (HF) and left bundle branch block (LBBB); however, up to 30% of patients in this selected group are nonresponders.

Hypothesis

We hypothesized that clinical and echocardiographic variables can be used to develop a simple mortality risk stratification score in CRT.

Methods

Best-subsets proportional-hazards regression analysis was used to develop a simple clinical risk score for all-cause mortality in 756 patients with LBBB allocated to the CRT with defibrillator (CRT-D) group enrolled in the multicenter automatic defibrillator implantation trial with cardiac resynchronization therapy. The score was used to assess the mortality risk within the CRT-D group and the associ

SUBMITTER: Biton Y 

PROVIDER: S-EPMC6490024 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature