Incidence of thromboembolic and bleeding events in patients with newly diagnosed nonvalvular atrial fibrillation: An Asian multicenter retrospective cohort study in Singapore.

ABSTRACT:

Background

Real-world effectiveness and safety of antithrombotics in nonvalvular atrial fibrillation (NVAF) patients in Singapore has not been thoroughly studied.

Hypothesis

Users of various antithrombotics experience a significantly different risk of stroke and major bleed compared with warfarin users.

Methods

This multicenter retrospective cohort study included patients age ≥ 21 years newly diagnosed with NVAF between July 2012 and September 2015. Using electronic medical records, data on patients' demographics, antithrombotics prescribed, and CHA₂ DS₂ -VASc and HAS-BLED risk factors were collected. Patients were followed for 1 year from diagnosis for the primary effectiveness and safety endpoints of incident stroke or systemic embolism and maj

SUBMITTER: Wee XT 

PROVIDER: S-EPMC6490354 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature