Association between echocardiographic epicardial fat thickness and circulating endothelial progenitor cell level in patients with stable angina pectoris.

ABSTRACT:

Background

Epicardial adipose tissue is associated with coronary artery disease (CAD). Circulating endothelial progenitor cell (EPC) level represents a marker of endothelial dysfunction and vascular health. However, the relationship between epicardial fat and circulating EPC remains unknown. This study aimed to investigate association between echocardiographic epicardial fat thickness (EFT) and circulating EPC level.

Hypothesis

Epicardial fat causes inflammation and contributes to progression of CAD.

Methods

We enrolled 213 consecutive patients with stable angina, and EFT was determined by echocardiography. Quantification of EPC markers (defined as CD34 ⁺ , CD34 ⁺ KDR ⁺ , CD34 ⁺ KDR ⁺ CD133 ⁺ cells) in

SUBMITTER: Chang TY 

PROVIDER: S-EPMC6490635 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature