Preterm birth and risk of chronic kidney disease from childhood into mid-adulthood: national cohort study.

ABSTRACT:

Objective

To investigate the relation between preterm birth (gestational age <37 weeks) and risk of CKD from childhood into mid-adulthood.

Design

National cohort study.

Setting

Sweden.

Participants

4 186 615 singleton live births in Sweden during 1973-2014.

Exposures

Gestational age at birth, identified from nationwide birth records in the Swedish birth registry.

Main outcome measures

CKD, identified from nationwide inpatient and outpatient diagnoses through 2015 (maximum age 43 years). Cox regression was used to examine gestational age at birth and risk of CKD while adjusting for potential confounders, and co-sibling analyses assessed the influence of unmeasured shared familial (genetic or environmental) factors.

Results

4305 (0.1%) partic

SUBMITTER: Crump C 

PROVIDER: S-EPMC6490674 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature