Effect of communicating personalized rheumatoid arthritis risk on concern for developing RA: A randomized controlled trial.

ABSTRACT:

Objective

To investigate the effect of providing comprehensive personalized risk information on concern for chronic disease development.

Methods

Unaffected first-degree relatives (FDRs) of rheumatoid arthritis (RA) patients (n = 238) were randomly allocated to: 1) disclosure of RA risk personalized to demographics, genetics, biomarkers, and behaviors using a web-based tool (PRE-RA arm, n = 78); 2) PRE-RA with interpretation by a health educator (PRE-RA Plus arm, n = 80); and 3) standard RA education (Comparison arm, n = 80). Concern for developing RA was assessed at baseline and immediately, 6 weeks, 6 months, and 12 months post-intervention.

Results

FDRs randomized to PRE-RA arms were less concerned about developing RA than the Comparison arm at all post-intervention

SUBMITTER: Marshall AA 

PROVIDER: S-EPMC6491232 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature