Assortative Mating on Ancestry-Variant Traits in Admixed Latin American Populations.

ABSTRACT: Assortative mating is a universal feature of human societies, and individuals from ethnically diverse populations are known to mate assortatively based on similarities in genetic ancestry. However, little is currently known regarding the exact phenotypic cues, or their underlying genetic architecture, which inform ancestry-based assortative mating. We developed a novel approach, using genome-wide analysis of ancestry-specific haplotypes, to evaluate ancestry-based assortative mating on traits whose expression varies among the three continental population groups - African, European, and Native American - that admixed to form modern Latin American populations. Application of this method to genome sequences sampled from Colombia, Mexico, Peru, and Puerto Rico revealed widespread ancestry-base

SUBMITTER: Norris ET 

PROVIDER: S-EPMC6491930 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature