Modelling continuous abstinence rates over time from clinical trials of pharmacological interventions for smoking cessation.

ABSTRACT:

Background and aim

It is useful, for theoretical and practical reasons, to be able to specify functions for continuous abstinence over time in smoking cessation attempts. This study aimed to find the best-fitting models of mean proportion abstinent with different smoking cessation pharmacotherapies up to 52 weeks from the quit date.

Methods

We searched the Cochrane Database of Systematic Reviews to identify randomized controlled trials (RCTs) of pharmacological treatments to aid smoking cessation. For comparability, we selected trials that provided 12 weeks of treatment. Continuous abstinence rates for each treatment at each follow-up point in trials were extracted along with methodological details of the trial. Data points for each pharmacotherapy at each follow-up point we

SUBMITTER: Jackson SE 

PROVIDER: S-EPMC6492005 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature