Maternal complications following open and fetoscopic fetal surgery: A systematic review and meta-analysis.

ABSTRACT:

Objective

To establish maternal complication rates for fetoscopic or open fetal surgery.

Methods

We conducted a systematic literature review for studies of fetoscopic or open fetal surgery performed since 1990, recording maternal complications during fetal surgery, the remainder of pregnancy, delivery, and after the index pregnancy.

Results

One hundred sixty-six studies were included, reporting outcomes for open fetal (n = 1193 patients) and fetoscopic surgery (n = 9403 patients). No maternal deaths were reported. The risk of any maternal complication in the index pregnancy was 20.9% (95%CI, 15.22-27.13) for open fetal and 6.2% (95%CI, 4.93-7.49) for fetoscopic surgery. For severe maternal complications (grades III to V Clavien-Dindo classification of surgical complic

SUBMITTER: Sacco A 

PROVIDER: S-EPMC6492015 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature