Clostridium difficile isolated from faecal samples in patients with ulcerative colitis.

ABSTRACT:

Background

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is widely identified worldwide. This study aimed to investigate the phenotypic characterization and molecular typing of Clostridium difficile isolates among patients with UC at an inflammatory bowel disease clinic in Iran.

Methods

In this cross-sectional study, conducted from April 2015 to December 2015, 85 UC patients were assessed for C.difficile infection (CDI). C. difficile isolates were characterized based on their toxin profile and antimicrobial resistance pattern. Multi-locus sequence typing analysis (MLST) and PCR ribotyping were performed to define the genetic relationships between different lineages of toxigenic strains.

Results

The prevalence of C. difficile isolates was 31.8% (2

SUBMITTER: Shoaei P 

PROVIDER: S-EPMC6492486 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature