Enlarged perivascular spaces are associated with health-related quality of life in patients with acute ischemic stroke.

ABSTRACT:

Aims

This study explored the association between enlarged perivascular spaces (EPVS) and the health-related quality of life (HRQoL) in patients with acute ischemic stroke.

Methods

This was an observational study of consecutively screened patients with acute ischemic stroke from March 2010 to March 2015. EPVS were rated in the basal ganglia and the centrum semiovale with a validated scale. The HRQoL was assessed 3 months after the stroke onset using the Stroke-Specific Quality of Life (SSQoL). Linear regression models were used to study the association between EPVS and HRQoL.

Results

The study included 648 patients (mean age 65.8 years; 40.0% women) with mild to moderately severe stroke (median NIHSS score 2), of whom 640 (98.8%) exhibited signs of small vessel disease

SUBMITTER: Liang Y 

PROVIDER: S-EPMC6492717 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature