Intracranial artery atherosclerosis and lumen dilation in cerebral small-vessel diseases: a high-resolution MRI Study.

ABSTRACT:

Background and aims

Using high-resolution magnetic resonance imaging (HR-MRI), we aimed to investigate the abnormalities of intracranial artery in relation to cerebral small-vessel diseases (SVD)-related ischemic stroke and white matter lesions (WMLs).

Methods

Routine cranial MRI and HR-MRI were performed on consecutive patients with a SVD-related acute deep brain infarct (DBI) in the territory of middle cerebral artery (MCA), patients with SVD-related WMLs, and age-matched controls. The presence and distribution of MCA plaque and the area of MCA lumen and wall were comparatively analyzed among the groups.

Results

A total of 2340 image slices of 260 vessels in 130 subjects (57 with an acute DBI, 28 with WMLs, and 45 control subjects) were analyzed. In the patients wit

SUBMITTER: Xu WH 

PROVIDER: S-EPMC6493086 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature