Ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean section: an updated meta-analysis.

ABSTRACT:

Aims

A systematic literature review comparing the efficacy of ephedrine and phenylephrine for the management of spinal anesthesia-induced hypotension during Cesarean sections (C-sections) was published in 2002. A number of well-designed trials with controversial results have been published afterward. Therefore, an updated meta-analysis was necessary.

Methods

The MEDLINE, EMBASE, and the Cochrane Library databases were searched (last search performed on September 26, 2011). Pooled risk ratio (RR) or standard mean difference (SMD) and their 95% confidence intervals (95% CI) were calculated for the incidence of intra-operative hypotension or umbilical blood pH values.

Results

A total number of 15 trials and 742 parturients under elective C-sections were analyzed. When us

SUBMITTER: Lin FQ 

PROVIDER: S-EPMC6493492 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature