Complex Epidemiological Dynamics of Eastern Equine Encephalitis Virus in Florida.

ABSTRACT: Eastern equine encephalitis virus (EEEV) infection results in high mortality in infected horses and humans. Florida has been identified as an important source of EEEV epidemics to other states in the United States. In this study, we further characterized the epidemiological and evolutionary dynamics of EEEV in Florida. Epidemiological analysis of sentinel chicken seroconversion rates to EEEV infections during 2005-2016 suggested significant seasonality of EEEV activity in Florida. We observed significant annual activity of EEEV in the North and North Central regions, with little significant seasonality in the Panhandle region. Phylogenetic analysis of complete EEEV genome sequences from different host sources and regions in Florida during 1986-2014 revealed extensive genetic diversity and

SUBMITTER: Heberlein-Larson LA 

PROVIDER: S-EPMC6493969 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature