Accelerating chemical exchange saturation transfer MRI with parallel blind compressed sensing.

ABSTRACT:

Purpose

Chemical exchange saturation transfer is a novel and promising MRI contrast method, but it can be time-consuming. Common parallel imaging methods, like SENSE, can lead to reduced quality of CEST. Here, parallel blind compressed sensing (PBCS), combining blind compressed sensing (BCS) and parallel imaging, is evaluated for the acceleration of CEST in brain and breast.

Methods

The CEST data were collected in phantoms, brain (N = 3), and breast (N = 2). Retrospective Cartesian undersampling was implemented and the reconstruction results of PBCS-CEST were compared with BCS-CEST and k-t sparse-SENSE CEST. The normalized RMSE and the high-frequency error norm were used for quantitative comparison.

Results

In phantom and in vivo brain experiments, the acceleration fa

SUBMITTER: She H 

PROVIDER: S-EPMC6497066 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature