Atopic eczema and major cardiovascular outcomes: A systematic review and meta-analysis of population-based studies.

ABSTRACT:

Background

Atopic eczema is a common inflammatory skin disease. Various inflammatory conditions have been linked to cardiovascular disease, a major cause of global mortality and morbidity.

Objective

We sought to systematically review and meta-analyze population-based studies assessing associations between atopic eczema and specific cardiovascular outcomes.

Methods

MEDLINE, Embase, and Global Health were searched from inception to December 2017. We obtained pooled estimates using random-effects meta-analyses. We used a multivariate Bayesian meta-regression model to estimate the slope of effect of increasing atopic eczema severity on cardiovascular outcomes.

Results

Nineteen relevant studies were included. The effects of atopic eczema reported in cross-sectional

SUBMITTER: Ascott A 

PROVIDER: S-EPMC6497108 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature