Lipid based nutrient supplements during pregnancy may improve foetal growth in HIV infected women - A cohort study.

ABSTRACT:

Objectives

Both maternal HIV infection and antiretroviral therapy are associated with adverse birth outcomes. The role of antenatal nutrient supplements with regard to adverse birth outcomes in HIV infected women exposed to antiretroviral therapy is not well known. We assessed the association between HIV and birth outcomes and explored whether antenatal lipid-based nutrient supplements (LNS) modulated this association.

Methods

We analysed a nested cohort of pregnant Malawian women who received daily LNS, multiple micronutrients (MMN) or iron and folic acid (IFA). Birth weight, length-for-age z-score (LAZ) and weight-for-age z-score (WAZ) were analysed as continuous outcomes and proportion of stunting and small-for-gestational age (SGA) as dichotomous outcomes.

Results

SUBMITTER: Nkhoma M 

PROVIDER: S-EPMC6497372 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature