Inflammation and infections in unreported chronic obstructive pulmonary disease exacerbations.

ABSTRACT: Purpose: COPD patients often do not report acute exacerbations to healthcare providers - unreported exacerbations. It is not known whether variances in symptoms, airway obstruction, aetiology and inflammatory responses account for differences in reporting of COPD exacerbations. The aims of the study were to compare symptoms, lung function changes, aetiology and inflammatory markers between exacerbations that were reported to healthcare providers or treated, with those that were unreported and untreated. Patients and methods: We recruited a cohort of COPD patients and collected clinical data and blood and airway samples when stable and during acute exacerbations. Virological and bacterial analyses were carried out and inflammatory markers measured. Results: We found no

SUBMITTER: Calderazzo MA 

PROVIDER: S-EPMC6497477 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature