The physiological determinants of near-infrared spectroscopy-derived regional cerebral oxygenation in critically ill adults.

ABSTRACT:

Background

To maintain adequate oxygen delivery to tissue, resuscitation of critically ill patients is guided by assessing surrogate markers of perfusion. As there is no direct indicator of cerebral perfusion used in routine critical care, identifying an accurate strategy to monitor brain perfusion is paramount. Near-infrared spectroscopy (NIRS) is a non-invasive technique to quantify regional cerebral oxygenation (rSO₂) that has been used for decades during cardiac surgery which has led to targeted algorithms to optimize rSO₂ being developed. However, these targeted algorithms do not exist during critical care, as the physiological determinants of rSO₂ during critical illness remain poorly understood.

Materials and methods

This prospective o

SUBMITTER: Wood MD 

PROVIDER: S-EPMC6497723 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature