Anti-Ebola therapy for patients with Ebola virus disease: a systematic review.

ABSTRACT:

Background

Management of Ebola virus disease (EVD) has historically focused on infection prevention, case detection and supportive care. Several specific anti-Ebola therapies have been investigated, including during the 2014-2016 West African outbreak. Our objective was to conduct a systematic review of the effect of anti-Ebola virus therapies on clinical outcomes to guide their potential use and future evaluation.

Methods

We searched PubMed, EMBASE, Global Health, Cochrane Library, African Index Medicus, WHOLIS (inception-9 April 2018), and trial registries for observational studies or clinical trials, in any language, that enrolled patients with confirmed EVD who received therapy targeting Ebola virus and reported on mortality, symptom duration, or adverse effects.

Resu

SUBMITTER: Lee JS 

PROVIDER: S-EPMC6498552 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature