Serum GP73 predicts posthepatectomy outcomes in patients with hepatocellular carcinoma.

ABSTRACT:

Background and aims

Serum GP73 is a useful biomarker in assessing hepatic fibrosis degree. The aim of this study was to evaluate the predictive value of serum GP73 level for posthepatectomy short-term outcomes in hepatocellular carcinoma (HCC) patients.

Methods

A total of 280 patients undergoing liver resection for HCC between October 2015 and April 2018 were included in this study. Detailed preoperative clinicopathological data were collected and GP73 levels in serum obtained the day before hepatectomy were examined. Receiver operating characteristic (ROC) analysis was used to calculate the optimal cutoff of GP73, and independent risk factors for postoperative outcomes was assessed by logistic regression model.

Results

The mean GP73 level in patients was 111.8 ± 153.

SUBMITTER: Ke MY 

PROVIDER: S-EPMC6498666 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature