Preoperative Statin Use Not Associated With Improved Outcomes After Ascending Aortic Repair.

ABSTRACT: Statins have potent pleiotropic effects that have been correlated with improved perioperative cardiovascular surgery outcomes. We hypothesize that statins may improve morbidity and mortality after ascending aortic surgery. Within a statewide database consisting of 19 centers a total of 1804 patients had ascending aortic repair with or without aortic valve replacement (2004-2016). Patients were stratified by preoperative statin therapy for analysis. To account for baseline differences, patients were propensity matched in a 1:1 fashion by baseline characteristics. Patient characteristics and outcomes were analyzed by paired analysis. Of 1804 patients undergoing ascending aortic repair, 35% took statins preoperatively. After matching, 386 patients in each group were well matched with no stati

SUBMITTER: Tyerman Z 

PROVIDER: S-EPMC6498844 | biostudies-literature | 2018 Winter

REPOSITORIES: biostudies-literature