Optimal Electrode Size for Multi-Scale Extracellular-Potential Recording From Neuronal Assemblies.

ABSTRACT: Advances in microfabrication technology have enabled the production of devices containing arrays of thousands of closely spaced recording electrodes, which afford subcellular resolution of electrical signals in neurons and neuronal networks. Rationalizing the electrode size and configuration in such arrays demands consideration of application-specific requirements and inherent features of the electrodes. Tradeoffs among size, spatial density, sensitivity, noise, attenuation, and other factors are inevitable. Although recording extracellular signals from neurons with planar metal electrodes is fairly well established, the effects of the electrode characteristics on the quality and utility of recorded signals, especially for small, densely packed electrodes, have yet to be fully characterize

SUBMITTER: Viswam V 

PROVIDER: S-EPMC6498989 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature