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Long-Term Change in both Dietary Insulinemic and Inflammatory Potential Is Associated with Weight Gain in Adult Women and Men.


ABSTRACT:

Background

The influence of long-term dietary patterns on weight gain and the underlying potential biological mechanisms are not fully understood.

Objective

We prospectively examined the association of changes in 2 empirical hypothesis-oriented dietary patterns (insulinemic and inflammatory) and weight gain over 24 y at 4-y intervals.

Methods

We followed 54,397 women in the Nurses' Health Study and 33,043 men in the Health Professionals Follow-Up Study (1986-2010), and computed the empirical dietary index for hyperinsulinemia (EDIH) and empirical dietary inflammatory pattern (EDIP) scores from food frequency questionnaires administered every 4 y. Both scores are weighted sums of 18 food groups, which characterize dietary insulinemic or inflammatory potential based on

SUBMITTER: Tabung FK 

PROVIDER: S-EPMC6499102 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature