Association of Statin Use and High Serum Cholesterol Levels With Risk of Primary Open-Angle Glaucoma.

ABSTRACT:

Importance

The use of statins (hydroxymethylglutaryl coenzyme A inhibitors) has been associated with a lower risk of primary open-angle glaucoma (POAG); however, results have been conflicting, and little is known about the association between high cholesterol levels and POAG.

Objective

To assess the association of elevated cholesterol levels and statin use with incident POAG.

Design, setting, and participants

This study used data collected biennially from participants aged 40 years or older who were free of glaucoma and reported eye examinations, within 3 population-based cohorts: the Nurses' Health Study (N = 50 710; followed up from 2000 to 2014), the Nurses' Health Study 2 (N = 62 992; 1999-2015), and the Health Professionals Follow-up Study (N = 23 080; 2000-2014)

SUBMITTER: Kang JH 

PROVIDER: S-EPMC6499123 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature