Optical Coherence Tomography Segmentation Errors of the Retinal Nerve Fiber Layer Persist Over Time.

ABSTRACT: PRéCIS:: There are errors in automated segmentation of the retinal nerve fiber layer (RNFL) in glaucoma suspects or patients with mild glaucoma that appear to persist over time; however, automated segmentation has greater repeatability than manual segmentation.

Purpose

To identify whether optical coherence tomography (OCT) segmentation errors in RNFL thickness measurements persist longitudinally.

Methods

This was a cohort study. We used spectral domain OCT (Spectralis) to measure RNFL thickness in a 6-degree peripapillary circle, and exported the native "automated segmentation only" results. In addition, we exported RNFL thickness results after "manual refinement" to correct errors in the automated segmentation, and used the differences in these measurements as "error" in seg

SUBMITTER: Nagarkatti-Gude N 

PROVIDER: S-EPMC6499633 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature