Effect of triploidy on liver gene expression in coho salmon (Oncorhynchus kisutch) under different metabolic states.

ABSTRACT:

Background

Triploid coho salmon are excellent models for studying gene dosage and the effects of increased cell volume on gene expression. Triploids have an additional haploid genome in each cell and have fewer but larger cells than diploid coho salmon to accommodate the increased genome size. Studying gene expression in triploid coho salmon provides insight into how gene expression may have been affected after the salmonid-specific genome duplication which occurred some 90 MYA. Triploid coho salmon are sterile and consequently can live longer and grow larger than diploid congeners in many semelparous species (spawning only once) because they never reach maturity and post-spawning mortality is averted. Triploid fishes are also of interest to the commercial sector (larger fish are m

SUBMITTER: Christensen KA 

PROVIDER: S-EPMC6500012 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature