Off-label drug prescriptions in French general practice: a cross-sectional study.

ABSTRACT:

Objectives

Off-label drug prescribing is a public health and economic issue. The aim of this study was to describe off-label prescription in general practice in France, in terms of frequency and nature, and to identify its main determining factors.

Design

Multicentre cross-sectional study SETTING: Twenty-three training general practice offices PARTICIPANTS: All the voluntary patients coming for a medical consultation or visited at home over a cumulative period of 5 days per office between November 2015 and January 2016.

Methods

Eleven interns, acting as observers, collected data. Two reviewers analysed the drugs prescribed by the trainers, in order to identify those prescribed off-label in terms of their indication or the age of the patient. We used a univariate, then

SUBMITTER: Drogou F 

PROVIDER: S-EPMC6500201 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature