Cost-effectiveness of faecal calprotectin used in primary care in the diagnosis of inflammatory bowel disease.

ABSTRACT:

Objective

Inflammatory bowel disease (IBD) is a chronic, autoimmune, gastrointestinal disorder. Canada has one of the highest prevalence and incidence rates of IBD in the world. Diagnosis is challenging due to the similarity of symptoms to functional gastrointestinal disorders. Faecalcalprotectin (FC) is a biomarker for active mucosal inflammation and has proven effective in the diagnosis of IBD. Our study objective was to assess the cost-effectiveness of adding an FC test compared with standard practice (blood test) in primary care among adult patients presenting with gastrointestinal symptoms.

Design

We constructed a decision analytic tree with a 1-year time horizon. The cut-off level of 100 µg/g was used for FC testing. Probabilistic analyses were conducted for the base c

SUBMITTER: Zhang W 

PROVIDER: S-EPMC6500206 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature