Abdominal aortic calcification, bone mineral density and fractures: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Abdominal aortic calcification (AAC) is associated with low bone mass and increased fracture risk. Two previous meta-analyses have investigated the association between AAC and fracture. However, these meta-analyses only identified articles until December 2016, undertook limited searches and did not explore potential sources of between-study heterogeneity. We aim to undertake a sensitive and comprehensive assessment of the relationship between AAC, bone mineral density (BMD) as well as prevalent and incident fractures.

Methods

We will search MEDLINE, EMBASE, Web of Science core collection and Google Scholar (top 200 articles sorted by relevance) from their inception to 1 June 2018. Reference lists of included studies and previous systematic reviews will be hand s

SUBMITTER: Rodriguez AJ 

PROVIDER: S-EPMC6500258 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature