Oral anticoagulation therapy use in patients with atrial fibrillation after the introduction of non-vitamin K antagonist oral anticoagulants: findings from the French healthcare databases, 2011-2016.

ABSTRACT:

Objectives

To describe (i) the trend in oral anticoagulant (OAC) use following the introduction of non-vitamin K antagonist oral anticoagulant (NOAC) therapy for stroke prevention in atrial fibrillation (AF) patients and (ii) the current patterns of use of NOAC therapy in new users with AF in France.

Design

(i) Repeated cross-sectional study and (ii) population-based cohort study.

Setting

French national healthcare databases (50 million beneficiaries).

Participants

(i) Patients with identified AF in 2011, 2013 and 2016 and (ii) patients with AF initiating OAC therapy in 2015-2016. PRIMARY AND SECONDARY OUTCOME MEASURES: (i) Trend in OAC therapy use in patients with AF and (ii) patterns of use of NOAC therapy in new users with AF.

Results

Between 2011 and

SUBMITTER: Maura G 

PROVIDER: S-EPMC6500377 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature