Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis.

ABSTRACT:

Importance

The death of a pediatric patient with sepsis motivated New York to mandate statewide sepsis treatment in 2013. The mandate included a 1-hour bundle of blood cultures, broad-spectrum antibiotics, and a 20-mL/kg intravenous fluid bolus. Whether completing the bundle elements within 1 hour improves outcomes is unclear.

Objective

To determine the risk-adjusted association between completing the 1-hour pediatric sepsis bundle and individual bundle elements with in-hospital mortality.

Design, settings, and participants

Statewide cohort study conducted from April 1, 2014, to December 31, 2016, in emergency departments, inpatient units, and intensive care units across New York State. A total of 1179 patients aged 18 years and younger with sepsis and septic shock re

SUBMITTER: Evans IVR 

PROVIDER: S-EPMC6500448 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature