Active surveillance for prostate and thyroid cancers: evolution in clinical paradigms and lessons learned.

ABSTRACT: The adverse effects of overdiagnosis and overtreatment observed in men with clinically insignificant prostate cancers after the introduction of prostate-specific antigen-based screening are now being observed in those with thyroid cancer, owing to the introduction of new imaging technologies. Thus, the evolving paradigm of active surveillance in prostate and thyroid cancers might be valuable in informing the development of future active surveillance protocols. The lessons learned from active surveillance and their implications include the need to minimize the use of broad, population-based screening programmes that do not incorporate patient education and the need for individualized or shared decision-making, which can decrease the extent of overtreatment. Furthermore, from the experience

SUBMITTER: Lowenstein LM 

PROVIDER: S-EPMC6501050 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature