Rotavirus vaccine impact assessment surveillance in India: protocol and methods.

ABSTRACT:

Introduction

Rotavirus infection accounts for 39% of under-five diarrhoeal deaths globally and 22% of these deaths occur in India. Introduction of rotavirus vaccine in a national immunisation programme is considered to be the most effective intervention in preventing severe rotavirus disease. In 2016, India introduced an indigenous rotavirus vaccine (Rotavac) into the Universal Immunisation Programme in a phased manner. This paper describes the protocol for surveillance to monitor the performance of rotavirus vaccine following its introduction into the routine childhood immunisation programme.

Methods

An active surveillance system was established to identify acute gastroenteritis cases among children less than 5 years of age. For all children enrolled at sentinel sites, case

SUBMITTER: Nair NP 

PROVIDER: S-EPMC6502045 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature