Usefulness of the heparin-binding protein level to diagnose sepsis and septic shock according to Sepsis-3 compared with procalcitonin and C reactive protein: a prospective cohort study in China.

ABSTRACT:

Objectives

Our aim was to assess the release level of heparin-binding protein (HBP) in sepsis and septic shock under the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Design

Prospective cohort study.

Setting

A general teaching hospital in China.

Participants

Adult infected patients with suspected sepsis and people who underwent physical examination were included. According to the health status and severity of illness, the research subjects were divided into healthy, local infection, sepsis non-shock and septic shock under Sepsis-3 definitions.

Main outcome measures

Plasma levels of HBP, procalcitonin (PCT), C reactive protein (CRP) and complete blood count were detected in all subjects. Single-factor analysis of

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC6502053 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature