ABO blood type and risk of porcine bioprosthetic aortic valve degeneration: SWEDEHEART observational cohort study.

ABSTRACT:

Objective

Blood type A antigen on porcine aortic bioprostheses might initiate an immune reaction leading to an increased frequency of structural valve deterioration in patients with blood type B or O. The aim was to analyse the association between ABO blood type and porcine bioprosthetic aortic valve degeneration.

Design

Observational nationwide cohort study.

Setting

Swedish population-based study.

Participants

Adult patients (n=3417) who underwent surgical aortic valve replacement and received porcine bioprosthetic aortic valves between 1995 and 2012 from the Swedish Web system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies register. The study database was enriched with information from othe

SUBMITTER: Persson M 

PROVIDER: S-EPMC6502064 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature