Micro/nano-hierarchical structured TiO₂ coating on titanium by micro-arc oxidation enhances osteoblast adhesion and differentiation.

ABSTRACT: Nano-structured and micro/nano-hierarchical structured TiO₂ coatings were produced on polished titanium by the micro-arc oxidation (MAO) technique. This study was conducted to screen a suitable structured TiO₂ coating for osteoblast adhesion and differentiation in dental implants. The formulation was characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and wettability testing. Adhesion, proliferation and osteogenic differentiation of MG63 cells were analysed by SEM, Cell Counting Kit-8 (CCK-8) and quantitative real-time PCR. The micro/nano-hierarchical structured TiO₂ coating with both slots and pores showed the best morphology and wettability. XRD analysis revealed that rutile predominated along with a minor amount of anatase in bot

SUBMITTER: Pan X 

PROVIDER: S-EPMC6502366 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature