Cardiac Baroreflex, HRV, and Statistics: An Interdisciplinary Approach in Hypertension.

ABSTRACT: Interests about the fine underpinnings of cardiovascular beat-by-beat variability have historical roots. Over the last decades, various aspects of the relationships between arterial pressure and heart period were taken as a proxy of the baroreflex in physiology and medicine, stimulating the interest of investigators in several interconnected scientific fields, in particular, bioengineering, neurophysiology, and clinical medicine. Studies of the overall system facilitated the emergence of a simplified negative (vagal) feedback model of the baroreflex and overshadowed the simultaneous interaction with excitatory, sympathetic positive-feedback mechanisms that would, however, better suit the model of a "paired antagonistic (parasympathetic/sympathetic) innervation of the internal organs." From

SUBMITTER: Solaro N 

PROVIDER: S-EPMC6503090 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature