Clinical and molecular epidemiology of Crimean-Congo hemorrhagic fever in Oman.

ABSTRACT:

Background

Crimean-Congo hemorrhagic fever (CCHF) is a serious disease with a high fatality rate reported in many countries. The first case of CCHF in Oman was detected in 1995 and serosurveys have suggested widespread infection of humans and livestock throughout the country.

Methodology

Cases of CCHF reported to the Ministry of Health (MoH) of Oman between 1995 and 2017 were retrospectively reviewed. Diagnosis was confirmed by serology and/or molecular tests in Oman. Stored RNA from recent cases was studied by sequencing the complete open reading frame (ORF) of the viral S segment at Public Health England, enabling phylogenetic comparisons to be made with other S segments of strains obtained from the region.

Findings

Of 88 cases of CCHF, 4 were sporadic in 1995 and 1

SUBMITTER: Al-Abri SS 

PROVIDER: S-EPMC6504112 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature