Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach.

ABSTRACT: Cancer is one of the most complex diseases that has resulted in multiple genetic disorders and cellular abnormalities. Globally, cancer is the most common health concern disease that is affecting human beings. Great efforts have been made over the past decades in biology with the aim of searching novel and more efficient tools in therapy. Thus, small interfering RNAs (siRNAs) have been considered one of the most noteworthy developments which are able to regulate gene expression following a process known as RNA interference (RNAi). RNAi is a post-transcriptional mechanism that involves the inhibition of gene expression through promoting cleavage on a specific area of a target messenger RNA (mRNA). This technology has shown promising therapeutic results for a good number of diseases, especia

SUBMITTER: Mahmoodi Chalbatani G 

PROVIDER: S-EPMC6504672 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature