The association between histological subtype of a first primary endometrial cancer and second cancer risk.

ABSTRACT: OBJECTIVE:To evaluate the risk of a second primary cancer after endometrial cancer according to histological subtype. METHODS:Using data from the 13 National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) registries we identified women diagnosed with a primary endometrial cancer between 1992 and 2014. We calculated standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) for second primary cancer risk (all anatomical sites combined and for individual anatomical sites) among patients with endometrial cancer compared with the general population, in the overall study population and according to histological subtype. RESULTS:Among 96 256 women diagnosed with endometrial cancer, 8.4% (n=8083) developed a second primary cancer. The risk of second primary can

SUBMITTER: Rhoades J 

PROVIDER: S-EPMC6504982 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature